Kari Byron graduated from Los Gatos High School and went on
to study film and sculpture at San Francisco State University,
from which she graduated Magna Cum Laude with a Bachelor of Arts
degree in Film and Sculpture in May 1998. After this, Kari Byron
spent the following year backpacking mostly in south-east Asia,
such as the Himalayas, and was also involved in a number of art
Byron is best known for her appearances on the Discovery Channel show MythBusters, where she assists Adam Savage and Jamie Hyneman with projects about the myths they bust, as well as doing myths with fellow build team members Tory Belleci and Grant Imahara. Kari Byron became involved in the show after persistently showing up at Hyneman's M5 Industries workshop in a desire to get hired at his company. On her first day, she was asked by Jamie and MythBusters producer Peter Rees to help out with the "vacuum plane toilet" myth. Kari Byron was given a more prominent role in the show starting with its second season. Not having had a long history in show business, at first Kari Byron found it hard to act naturally with this more visible position but gradually became more used to it.
Art and sculpturing are important aspects of her life, and Kari Byron has claimed that she does some kind of art every day, and thinks she would go crazy if she didn't. Some of her preferred sculpturing materials are polymer clay, various found objects, acrylic gouache, wood and metals. Kari showcases some of her art on her personal website, and photography from her public exhibit debut Stray Doll in September 2004 is available at Anno Domini. Kari Byron has found inspiration in artists such as various SECCA award winners in the past.  Preferring to make her audience think, she has had the following to say about her art:
"I do portraits or I make sculptures exploring my cynical view of contemporary issues. Artists that over-explain their art always take away from my experience as a viewer. I try to let my viewer make their own message. Art becomes more personal if you let yourself become involved. I will always explain my motivations and themes if someone asks but I prefer to hear theirs."
Kari Byron has also made guest appearances on The Late Show with David Letterman and Beyond Tomorrow, and appeared in a four-page spread in the June 2006 United States edition of FHM.
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